Comparison of chemical-induced temporomandibular osteoarthritis rat models (monosodium iodoacetate versus collagenase type II) for the study of prolonged drug delivery systems

Comparison of chemical-induced temporomandibular osteoarthritis rat models (monosodium iodoacetate versus collagenase type II) for the study of prolonged drug delivery systems

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<h4>Objective</h4> To compare two agents that can induce a rat model of temporomandibular joint osteoarthritis (TMJOA) by chemical induction: monosodium iodoacetate (MIA) and collagenase type 2 (Col-2). We wished to ascertain the best agent for assessing drug-delivery systems (DDSs). <...

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Bibliographic Details
Main Authors: Florent Barry, Feng Chai, Henry Chijcheapaza-Flores, Maria José Garcia-Fernandez, Nicolas Blanchemain, Romain Nicot
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9888674/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9888674/?tool=EBI

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