Diagnostic value of IHC and FISH methods for HER2 gene amplification detection in paraffin embedded blocks of breast cancer
Introduction: Breast cancer is the leading cause of malignancy related deaths in women worldwide. In 20%-30% of breast cancers, HER2 gene amplification or overexpression is observed. Determination of HER2 amplification is performed mainly by IHC technique to measure its protein expression on the cel...
Main Authors: | , , |
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Format: | Article |
Language: | fas |
Published: |
Mashhad University of Medical Sciences
2023-01-01
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Series: | Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān |
Subjects: | |
Online Access: | https://ijogi.mums.ac.ir/article_21644_f2d686b02baa1c7efc6b2436c2d2c264.pdf |