Diagnostic value of IHC and FISH methods for HER2 gene amplification detection in paraffin embedded blocks of breast cancer

Introduction: Breast cancer is the leading cause of malignancy related deaths in women worldwide. In 20%-30% of breast cancers, HER2 gene amplification or overexpression is observed. Determination of HER2 amplification is performed mainly by IHC technique to measure its protein expression on the cel...

Full description

Bibliographic Details
Main Authors: Seyed Ahmad Aleyasin, Esmaeil Akbari, Fatemeh Saadati
Format: Article
Language:fas
Published: Mashhad University of Medical Sciences 2023-01-01
Series:Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān
Subjects:
Online Access:https://ijogi.mums.ac.ir/article_21644_f2d686b02baa1c7efc6b2436c2d2c264.pdf