Promising Therapy Candidates for Liver Fibrosis

Promising Therapy Candidates for Liver Fibrosis

Liver fibrosis is a wound-healing process in response to repeated and chronic injury to hepatocytes and/or cholangiocytes. Ongoing hepatocyte apoptosis or necrosis lead to increase in ROS production and decrease in antioxidant activity, which recruits inflammatory cells from the blood and activate h...

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Bibliographic Details
Main Authors: Ping eWang, Yukinori eKoyama, Xiao eLiu, Jun eXu, Shuang eLiang, IN HEE eKIM, David eBrenner, Tatiana eKisseleva
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-02-01
Series:Frontiers in Physiology
Subjects:
Hepatocytes
Inflammation
Myofibroblasts
liver fibrosis
cholangiocyte
early-phase clinical trial
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2016.00047/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2016.00047/full

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