UGT1A1 (TA)n promoter genotype: Diagnostic and population pharmacogenetic marker in Serbia

UGT1A1 (TA)n promoter genotype: Diagnostic and population pharmacogenetic marker in Serbia

The UGT1A1 enzyme is involved in the metabolism of bilirubin and numerous medications. Unconjugated hyperbilirubinemia, commonly presented as Gilbert syndrome (GS), is a result of decreased activity of the UGT1A1 enzyme, variable number of TA repeats in the promoter of the UGT1A1 gene affects enzyme...

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Bibliographic Details
Main Authors: Vukovic M, Radlovic N, Lekovic Z, Vucicevic K, Maric N, Kotur N, Gasic V, Ugrin M, Stojiljkovic M, Dokmanovic L, Zukic B, Pavlovic S
Format: Article
Language:English
Published: Sciendo 2018-10-01
Series:Balkan Journal of Medical Genetics
Subjects:
gilbert syndrome (gs)
unconjugated hyperbilirubinemia
population pharmacogenetics, ugt1a1 (ta)n promoter variants
Online Access:https://doi.org/10.2478/bjmg-2018-0012

Internet

https://doi.org/10.2478/bjmg-2018-0012

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