Mov10 suppresses retroelements and regulates neuronal development and function in the developing brain

Mov10 suppresses retroelements and regulates neuronal development and function in the developing brain

Abstract Background Moloney leukemia virus 10 (Mov10) is an RNA helicase that mediates access of the RNA-induced silencing complex to messenger RNAs (mRNAs). Until now, its role as an RNA helicase and as a regulator of retrotransposons has been characterized exclusively in cell lines. We investigate...

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Bibliographic Details
Main Authors: Geena Skariah, Joseph Seimetz, Miles Norsworthy, Monica C. Lannom, Phillip J. Kenny, Mohamed Elrakhawy, Craig Forsthoefel, Jenny Drnevich, Auinash Kalsotra, Stephanie Ceman
Format: Article
Language:English
Published: BMC 2017-06-01
Series:BMC Biology
Subjects:
RNA helicase
RISC
Brain
Neurite outgrowth
Embryonic development
Mov10
Online Access:http://link.springer.com/article/10.1186/s12915-017-0387-1

Internet

http://link.springer.com/article/10.1186/s12915-017-0387-1

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