Phosphorylation of USP29 by CDK1 Governs TWIST1 Stability and Oncogenic Functions

Phosphorylation of USP29 by CDK1 Governs TWIST1 Stability and Oncogenic Functions

Abstract Triple‐negative breast cancer (TNBC) is a highly lethal malignancy with limited therapy options. TWIST1, a key transcriptional factor of epithelial‐mesenchymal transition (EMT), contributes to self‐renewal of cancer stem‐like cells (CSCs), chemo‐resistance, metastasis, and TNBC‐related deat...

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Bibliographic Details
Main Authors: Tangming Guan, Mei Li, Yan Song, Jiayi Chen, Jiaxin Tang, Caishi Zhang, Yalei Wen, Xiao Yang, Lei Huang, Yingjie Zhu, Hongxian Wang, Ke Ding, Junxia Zheng, Haoxing Zhang, Tongzheng Liu
Format: Article
Language:English
Published: Wiley 2023-04-01
Series:Advanced Science
Subjects:
CDK1
chemotherapeutic resistance
metastasis
TWIST1
USP29
Online Access:https://doi.org/10.1002/advs.202205873

Internet

https://doi.org/10.1002/advs.202205873

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