Reinforcement versus fluidization in cytoskeletal mechanoresponsiveness.

Every adherent eukaryotic cell exerts appreciable traction forces upon its substrate. Moreover, every resident cell within the heart, great vessels, bladder, gut or lung routinely experiences large periodic stretches. As an acute response to such stretches the cytoskeleton can stiffen, increase trac...

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Bibliographic Details
Main Authors: Ramaswamy Krishnan, Chan Young Park, Yu-Chun Lin, Jere Mead, Richard T Jaspers, Xavier Trepat, Guillaume Lenormand, Dhananjay Tambe, Alexander V Smolensky, Andrew H Knoll, James P Butler, Jeffrey J Fredberg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2675060?pdf=render