Age-related decline in the expression of GDF9 and BMP15 genes in follicle fluid and granulosa cells derived from poor ovarian responders

Abstract Background Growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15) genes play important roles in folliculogenesis. Altered expression of the two have been found among patients with poor ovarian response (POR). In this prospective cohort study, we have determined the...

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Bibliographic Details
Main Authors: Yan Gong, Jesse Li-Ling, Dongsheng Xiong, Jiajing Wei, Taiqing Zhong, Hao Tan
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Journal of Ovarian Research
Subjects:
Online Access:https://doi.org/10.1186/s13048-020-00757-x