Osteopontin, Macrophage Migration Inhibitory Factor and Anti-Interleukin-8 Autoantibodies Complement CA125 for Detection of Early Stage Ovarian Cancer

Osteopontin, Macrophage Migration Inhibitory Factor and Anti-Interleukin-8 Autoantibodies Complement CA125 for Detection of Early Stage Ovarian Cancer

Early detection of ovarian cancer promises to reduce mortality. While serum CA125 can detect more than 60% of patients with early stage (I−II) disease, greater sensitivity might be observed with a panel of biomarkers. Ten protein antigens and 12 autoantibody biomarkers were measured in ser...

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Bibliographic Details
Main Authors: Jing Guo, Wei-Lei Yang, Daewoo Pak, Joseph Celestino, Karen H. Lu, Jing Ning, Anna E. Lokshin, Zhongping Cheng, Zhen Lu, Robert C. Bast
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Cancers
Subjects:
ovarian cancer
osteopontin (OPN)
macrophage migration inhibitory factor (MIF)
CA125
IL-8 autoantibodies (IL-8 AAb)
early detection
Online Access:https://www.mdpi.com/2072-6694/11/5/596

Internet

https://www.mdpi.com/2072-6694/11/5/596

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