Risk of chronic kidney disease in type 2 diabetes determined by polymorphisms in NOS3, APOB, KCNJ11, TCF7L2 genes as compound effect of risk genotypes combination

Genetic susceptibility plays an important role in the risk of developing chronic complications in patients with type 2 diabetes mellitus (T2DM). Aims. In this study, we evaluated the possible association of the polymorphic variants that encode key renal damage mediators (endothelial dysfunction, li...

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Main Authors: Anna Viktorovna Zheleznyakova, Nadezhda Olegovna Lebedeva, Olga Konstantinovna Vikulova, Valery Vyacheslavovich Nosikov, Minara Shamkhalovna Shamkhalova, Marina Vladimirovna Shestakova
Format: Article
Language:English
Published: Endocrinology Research Centre 2014-10-01
Series:Сахарный диабет
Subjects:
Online Access:https://www.dia-endojournals.ru/jour/article/view/6693