Multi-omics Analysis of the Intermittent Fasting Response in Mice Identifies an Unexpected Role for HNF4α

Summary: Every-other-day fasting (EODF) is an effective intervention for the treatment of metabolic disease, including improvements in liver health. But how the liver proteome is reprogrammed by EODF is currently unknown. Here, we use EODF in mice and multi-omics analysis to identify regulated pathw...

Full description

Bibliographic Details
Main Authors: Luke Hatchwell, Dylan J. Harney, Michelle Cielesh, Kieren Young, Yen Chin Koay, John F. O’Sullivan, Mark Larance
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720302126