Pathogen-based target attainment of optimized continuous infusion dosing regimens of piperacillin-tazobactam and meropenem in surgical ICU patients: a prospective single center observational study

Pathogen-based target attainment of optimized continuous infusion dosing regimens of piperacillin-tazobactam and meropenem in surgical ICU patients: a prospective single center observational study

Abstract Background Several studies have indicated that commonly used piperacillin-tazobactam (TZP) and meropenem (MEM) dosing regimens lead to suboptimal plasma concentrations for a range of pharmacokinetic/pharmacodynamic (PK/PD) targets in intensive care unit (ICU) patients. These targets are oft...

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Bibliographic Details
Main Authors: Thomas De Corte, Jarne Verhaeghe, Sofie Dhaese, Sarah Van Vooren, Jerina Boelens, Alain G. Verstraete, Veronique Stove, Femke Ongenae, Liesbet De Bus, Pieter Depuydt, Sofie Van Hoecke, Jan J. De Waele
Format: Article
Language:English
Published: SpringerOpen 2023-04-01
Series:Annals of Intensive Care
Subjects:
Piperacillin-tazobactam
Meropenem
Therapeutic drug monitoring
Continuous infusion
Online Access:https://doi.org/10.1186/s13613-023-01129-6

Internet

https://doi.org/10.1186/s13613-023-01129-6

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