Association Studies of HFE C282Y and H63D Variants with Oral Cancer Risk and Iron Homeostasis Among Whites and Blacks

Association Studies of HFE C282Y and H63D Variants with Oral Cancer Risk and Iron Homeostasis Among Whites and Blacks

Background: Polymorphisms in the hemochromatosis (HFE) gene are associated with excessive iron absorption from the diet, and pro-oxidant effects of iron accumulation are thought to be a risk factor for several types of cancer. Methods: The C282Y (rs1800562) and H63D (rs1799945) polymorphisms were ge...

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Bibliographic Details
Main Authors: Nathan R. Jones, Joseph H. Ashmore, Sang Y. Lee, John P. Richie, Philip Lazarus, Joshua E. Muscat
Format: Article
Language:English
Published: MDPI AG 2015-12-01
Series:Cancers
Subjects:
HFE
SNP
iron homeostasis
oral cancer
White
Black
genotyping
Online Access:http://www.mdpi.com/2072-6694/7/4/0898

Internet

http://www.mdpi.com/2072-6694/7/4/0898

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