Prolonged Lipid Accumulation in Cultured Primary Human Hepatocytes Rather Leads to ER Stress than Oxidative Stress

Prolonged Lipid Accumulation in Cultured Primary Human Hepatocytes Rather Leads to ER Stress than Oxidative Stress

Overweight has become a major health care problem in Western societies and is accompanied by an increasing incidence and prevalence of non-alcoholic fatty liver disease (NAFLD). The progression from NAFLD to non-alcoholic steatohepatitis (NASH) marks a crucial tipping point in the progression of sev...

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Bibliographic Details
Main Authors: Christiane Rennert, Theresa Heil, Gerda Schicht, Anna Stilkerich, Lena Seidemann, Victoria Kegel-Hübner, Daniel Seehofer, Georg Damm
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:International Journal of Molecular Sciences
Subjects:
liver
primary human hepatocytes
steatosis
NAFLD
NASH
ER stress
Online Access:https://www.mdpi.com/1422-0067/21/19/7097

Internet

https://www.mdpi.com/1422-0067/21/19/7097

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