Human Interleukine-1 receptor antagonist:Cloning, Expression and Optimization in E.coli Host

Human Interleukine-1 receptor antagonist:Cloning, Expression and Optimization in E.coli Host

Introduction & Objective: Interleukine-1 receptor antagonist (IL-1RA) is a powerful anti-inflammatory cytokine which limits the biological effects of IL-1. Due to structural similarity between IL-1 and its antagonist, IL-1RA competitively binds to IL-1 receptor which leads to no signal transduct...

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Bibliographic Details
Main Authors: Ghasem Barati, Hasan Mirza Hosseini, Jamshid Karimi, Fatemeh Ebrahimzadeh, Nooshin Shabab, Masoud Saidijam
Format: Article
Language:fas
Published: Hamadan University of Medical Sciences 2014-09-01
Series:پزشکی بالینی ابن سینا
Subjects:
arthritis
rheumatoid
cytokines
protein
recombinant
receptors
interleukin-1
Online Access:http://sjh.umsha.ac.ir/article-1-94-en.html

Internet

http://sjh.umsha.ac.ir/article-1-94-en.html

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