Ganoderma lucidum polysaccharide ameliorates cholesterol gallstone formation by modulating cholesterol and bile acid metabolism in an FXR-dependent manner

Abstract Background Cholesterol gallstone (CG) disease is a worldwide common disease characterized by cholesterol supersaturation in gallbladder bile. Ganoderma lucidum polysaccharide (GLP) has been shown to possess various beneficial effects against metabolic disorders. However, the role and underl...

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Bibliographic Details
Main Authors: Dan Huang, Shuang Shen, Qian Zhuang, Xin Ye, Yueqin Qian, Zhixia Dong, Xinjian Wan
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Chinese Medicine
Subjects:
Online Access:https://doi.org/10.1186/s13020-024-00889-y