Conformational dynamics of dynamin-like MxA revealed by single-molecule FRET
MxA (myxovirus resistance protein A) is a viral restriction factor whose activity depends on self-assembly into polymeric rings and helical filaments. Here the authors reveal the conformational movements involved in generating torque within polymeric MxA molecules and the dynamic conformational chan...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2017-05-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/ncomms15744 |