mtDNA extramitochondrial replication mediates mitochondrial defect effects

mtDNA extramitochondrial replication mediates mitochondrial defect effects

Summary: A high ratio of severe mitochondrial defects causes multiple human mitochondrial diseases. However, until now, the in vivo rescue signal of such mitochondrial defect effects has not been clear. Here, we built fly mitochondrial defect models by knocking down the essential mitochondrial genes...

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Bibliographic Details
Main Authors: Zhaoliang Shan, Shengnan Li, Yuxue Gao, Chunhua Jian, Xiuxiu Ti, Hui Zuo, Ying Wang, Guochun Zhao, Yan Wang, Qing Zhang
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:iScience
Subjects:
Biological sciences
Molecular biology
Molecular genetics
Molecular interaction
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224001913

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http://www.sciencedirect.com/science/article/pii/S2589004224001913

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