Hypoxia-induced DNA hypermethylation in human pulmonary fibroblasts is associated with Thy-1 promoter methylation and the development of a pro-fibrotic phenotype
<p>Abstract</p> <p>Background</p> <p>Pulmonary fibrosis is a debilitating and lethal disease with no effective treatment options. Understanding the pathological processes at play will direct the application of novel therapeutic avenues. Hypoxia has been implicated in th...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2012-08-01
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Series: | Respiratory Research |
Subjects: | |
Online Access: | http://respiratory-research.com/content/13/1/74 |