Hypoxia-induced DNA hypermethylation in human pulmonary fibroblasts is associated with Thy-1 promoter methylation and the development of a pro-fibrotic phenotype

<p>Abstract</p> <p>Background</p> <p>Pulmonary fibrosis is a debilitating and lethal disease with no effective treatment options. Understanding the pathological processes at play will direct the application of novel therapeutic avenues. Hypoxia has been implicated in th...

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Bibliographic Details
Main Authors: Robinson Claire M, Neary Roisin, Levendale Ashleigh, Watson Chris J, Baugh John A
Format: Article
Language:English
Published: BMC 2012-08-01
Series:Respiratory Research
Subjects:
Online Access:http://respiratory-research.com/content/13/1/74