Antiangiogenic agents targeting different angiogenic pathways have opposite effects on tumor hypoxia in R-18 human melanoma xenografts

Antiangiogenic agents targeting different angiogenic pathways have opposite effects on tumor hypoxia in R-18 human melanoma xenografts

Abstract Background Studies comparing the effect of antiangiogenic agents targeting different angiogenic pathways are sparse. The purpose of this study was to compare the effect of properdistatin and sunitinib treatment in a preclinical model of malignant melanoma. Properdistatin is a small peptide...

Full description

Bibliographic Details
Main Authors: Jon-Vidar Gaustad, Trude G. Simonsen, Lise Mari K. Andersen, Einar K. Rofstad
Format: Article
Language:English
Published: BMC 2017-06-01
Series:BMC Cancer
Subjects:
Malignant melanoma
Sunitinib
Properdistatin
Vascular morphology
Vascular function
Tumor hypoxia
Online Access:http://link.springer.com/article/10.1186/s12885-017-3404-4

Internet

http://link.springer.com/article/10.1186/s12885-017-3404-4

Similar Items