Integrin αvβ6 Promotes Lung Cancer Proliferation and Metastasis through Upregulation of IL-8–Mediated MAPK/ERK Signaling

Integrin αvβ6 Promotes Lung Cancer Proliferation and Metastasis through Upregulation of IL-8–Mediated MAPK/ERK Signaling

Lung cancer is notorious for high morbidity and mortality around the world. Interleukin (IL)-8, a proinflammatory chemokine with tumorigenic and proangiogenic effects, promotes lung cancer cells growth and migration and contributes to cell aggressive phenotypes. Integrin αvβ6 is a receptor of transm...

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Bibliographic Details
Main Authors: Pengwei Yan, Huanfeng Zhu, Li Yin, Lijun Wang, Peng Xie, Jinjun Ye, Xuesong Jiang, Xia He
Format: Article
Language:English
Published: Elsevier 2018-06-01
Series:Translational Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523317304643

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http://www.sciencedirect.com/science/article/pii/S1936523317304643

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