Inefficient antiviral response in reconstituted small-airway epithelium from chronic obstructive pulmonary disease patients following human parainfluenza virus type 3 infection

Inefficient antiviral response in reconstituted small-airway epithelium from chronic obstructive pulmonary disease patients following human parainfluenza virus type 3 infection

Abstract Chronic obstructive pulmonary disease (COPD) affects over 250 million individuals globally and stands as the third leading cause of mortality. Respiratory viral infections serve as the primary drivers of acute exacerbations, hastening the decline in lung function and worsening the prognosis...

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Bibliographic Details
Main Authors: Louise Bondeelle, Maud Salmona, Véronique Houdouin, Elise Diaz, Jacques Dutrieux, Séverine Mercier-Delarue, Samuel Constant, Song Huang, Anne Bergeron, Jérôme LeGoff
Format: Article
Language:English
Published: BMC 2024-04-01
Series:Virology Journal
Subjects:
Transcriptome
Respiratory virus
Pathogenesis
Airway epithelium
Online Access:https://doi.org/10.1186/s12985-024-02353-7

Internet

https://doi.org/10.1186/s12985-024-02353-7

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