Age, Sex Hormones, and Circadian Rhythm Regulate the Expression of Amyloid-Beta Scavengers at the Choroid Plexus

Accumulation of amyloid-beta (Aβ) in the brain is thought to derive from the impairment of Aβ clearance mechanisms rather than from its overproduction, which consequently contributes to the development of Alzheimer’s disease. The choroid plexus epithelial cells constitute an important clearance rout...

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Bibliographic Details
Main Authors: Ana C. Duarte, André Furtado, Mariya V. Hrynchak, Ana R. Costa, Daniela Talhada, Isabel Gonçalves, Manuel C. Lemos, Telma Quintela, Cecília R.A. Santos
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/21/18/6813