Additional value of a combined genetic risk score to standard cardiovascular stratification

Additional value of a combined genetic risk score to standard cardiovascular stratification

Abstract The utility of genetic risk scores (GRS) as independent risk predictors remains inconclusive. Here, we evaluate the additive value of a multi-locus GRS to the Framingham risk score (FRS) in coronary artery disease (CAD) risk prediction. A total of 2888 individuals (1566 coronary patients an...

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Bibliographic Details
Main Authors: Andreia Pereira, Maria Isabel Mendonca, Sofia Borges, Ana Célia Sousa, Sónia Freitas, Eva Henriques, Mariana Rodrigues, Ana Isabel Freitas, Graça Guerra, Carolina Freitas, Décio Pereira, António Brehm, Roberto Palma Dos Reis
Format: Article
Language:English
Published: Sociedade Brasileira de Genética
Series:Genetics and Molecular Biology
Subjects:
Coronary artery disease
genetic risk score
Framingham score
risk prediction
risk factors
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572018000500766&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572018000500766&lng=en&tlng=en

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