Modelling the complex nature of the tumor microenvironment: 3D tumor spheroids as an evolving tool

Abstract Cancer remains a serious burden in society and while the pace in the development of novel and more effective therapeutics is increasing, testing platforms that faithfully mimic the tumor microenvironment are lacking. With a clear shift from animal models to more complex in vitro 3D systems,...

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Bibliographic Details
Main Authors: Daniel B. Rodrigues, Rui L. Reis, Rogério P. Pirraco
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Journal of Biomedical Science
Subjects:
Online Access:https://doi.org/10.1186/s12929-024-00997-9