Natural blood feeding and temperature shift modulate the global transcriptional profile of Rickettsia rickettsii infecting its tick vector.

Rickettsia rickettsii is an obligate intracellular tick-borne bacterium that causes Rocky Mountain Spotted Fever (RMSF), the most lethal spotted fever rickettsiosis. When an infected starving tick begins blood feeding from a vertebrate host, R. rickettsii is exposed to a temperature elevation and to...

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Bibliographic Details
Main Authors: Maria Fernanda B M Galletti, André Fujita, Milton Y Nishiyama, Camila D Malossi, Adriano Pinter, João F Soares, Sirlei Daffre, Marcelo B Labruna, Andréa C Fogaça
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3796454?pdf=render