Polycomb Group Protein YY1 Is an Essential Regulator of Hematopoietic Stem Cell Quiescence

Polycomb Group Protein YY1 Is an Essential Regulator of Hematopoietic Stem Cell Quiescence

Summary: Yin yang 1 (YY1) is a ubiquitous transcription factor and mammalian polycomb group protein (PcG) with important functions to regulate embryonic development, lineage differentiation, and cell proliferation. YY1 mediates stable PcG-dependent transcriptional repression via recruitment of PcG p...

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Bibliographic Details
Main Authors: Zhanping Lu, Courtney C. Hong, Guangyao Kong, Anna L.F.V. Assumpção, Irene M. Ong, Emery H. Bresnick, Jing Zhang, Xuan Pan
Format: Article
Language:English
Published: Elsevier 2018-02-01
Series:Cell Reports
Subjects:
YY1
polycomb group protein
hematopoietic stem cell
cell cycle
quiescence
c-Kit
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718300433

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http://www.sciencedirect.com/science/article/pii/S2211124718300433

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