Associations between circulating cell-free mitochondrial DNA, inflammatory markers, and cognitive and physical outcomes in community dwelling older adults

Associations between circulating cell-free mitochondrial DNA, inflammatory markers, and cognitive and physical outcomes in community dwelling older adults

Abstract Background Dementia and frailty are common age-related syndromes often linked to chronic inflammation. Identifying the biological factors and pathways that contribute to chronic inflammation is crucial for developing new therapeutic targets. Circulating cell-free mitochondrial DNA (ccf-mtDN...

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Bibliographic Details
Main Authors: Lolita S. Nidadavolu, Danielle Feger, Diefei Chen, Yuqiong Wu, Francine Grodstein, Alden L. Gross, David A. Bennett, Jeremy D. Walston, Esther S. Oh, Peter M. Abadir
Format: Article
Language:English
Published: BMC 2023-05-01
Series:Immunity & Ageing
Subjects:
Cell-free DNA
Inflammation
sTNFR1
Mitochondria
Frailty
Dementia
Online Access:https://doi.org/10.1186/s12979-023-00342-y

Internet

https://doi.org/10.1186/s12979-023-00342-y

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