Investigation of intermediate CAG alleles of the HTT in the general population of Rio de Janeiro, Brazil, in comparison with a sample of Huntington disease‐affected families
Abstract Background Huntington disease (HD) (MIM: 143100) is a severe autosomal dominant neurodegenerative disease caused by the expansion of CAG trinucleotides (>35) in the HTT. Objective To investigate the frequency of intermediate CAG alleles (IAs) in individuals residing in Rio de Janeiro cit...
| المؤلفون الرئيسيون: | , , , |
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| التنسيق: | مقال |
| اللغة: | English |
| منشور في: |
Wiley
2020-04-01
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| سلاسل: | Molecular Genetics & Genomic Medicine |
| الموضوعات: | |
| الوصول للمادة أونلاين: | https://doi.org/10.1002/mgg3.1181 |