Predicting BRAFV600E mutations in papillary thyroid carcinoma using six machine learning algorithms based on ultrasound elastography

Abstract The most common BRAF mutation is thymine (T) to adenine (A) missense mutation in nucleotide 1796 (T1796A, V600E). The BRAFV600E gene encodes a protein-dependent kinase (PDK), which is a key component of the mitogen-activated protein kinase pathway and essential for controlling cell prolifer...

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Bibliographic Details
Main Authors: Enock Adjei Agyekum, Yu-guo Wang, Fei-Ju Xu, Debora Akortia, Yong-zhen Ren, Kevoyne Hakeem Chambers, Xian Wang, Jenny Olalia Taupa, Xiao-qin Qian
Format: Article
Language:English
Published: Nature Portfolio 2023-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-39747-6