Predicting BRAFV600E mutations in papillary thyroid carcinoma using six machine learning algorithms based on ultrasound elastography
Abstract The most common BRAF mutation is thymine (T) to adenine (A) missense mutation in nucleotide 1796 (T1796A, V600E). The BRAFV600E gene encodes a protein-dependent kinase (PDK), which is a key component of the mitogen-activated protein kinase pathway and essential for controlling cell prolifer...
Main Authors: | Enock Adjei Agyekum, Yu-guo Wang, Fei-Ju Xu, Debora Akortia, Yong-zhen Ren, Kevoyne Hakeem Chambers, Xian Wang, Jenny Olalia Taupa, Xiao-qin Qian |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-08-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-023-39747-6 |
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