The effect of sex and estrus cycle stage on optogenetic spreading depression induced migraine-like pain phenotypes

Abstract Background Migraine is more prevalent in females, raising the possibility that sex and gonadal hormones modulate migraine. We recently demonstrated that minimally invasive optogenetic spreading depolarization (opto-SD) elicits robust periorbital allodynia. The objective of this study was to...

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Bibliographic Details
Main Authors: Andrea M. Harriott, Angel Waruinge, Viola Appiah-Danquah, Leah Berhanu, Andreia Morais, Cenk Ayata
Format: Article
Language:English
Published: BMC 2023-07-01
Series:The Journal of Headache and Pain
Subjects:
Online Access:https://doi.org/10.1186/s10194-023-01621-1