Components of selection in the evolution of the influenza virus: linkage effects beat inherent selection.

The influenza virus is an important human pathogen, with a rapid rate of evolution in the human population. The rate of homologous recombination within genes of influenza is essentially zero. As such, where two alleles within the same gene are in linkage disequilibrium, interference between alleles...

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Bibliographic Details
Main Authors: Christopher J R Illingworth, Ville Mustonen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-12-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1003091&type=printable