Preclinical Assessment of Efficacy and Safety Analysis of CAR-T Cells (ISIKOK-19) Targeting CD19-Expressing B-Cells for the First Turkish Academic Clinical Trial with Relapsed/Refractory ALL and NHL Patients

Preclinical Assessment of Efficacy and Safety Analysis of CAR-T Cells (ISIKOK-19) Targeting CD19-Expressing B-Cells for the First Turkish Academic Clinical Trial with Relapsed/Refractory ALL and NHL Patients

Objective: Relapsed and refractory CD19-positive B-cell acute lymphoblastic leukemia (ALL) and non-Hodgkin lymphoma (NHL) are the focus of studies on hematological cancers. Treatment of these malignancies has undergone recent transformation with the development of new gene therapy and molecular biol...

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Bibliographic Details
Main Authors: Cihan Taştan, Derya Dilek Kançağı, Raife Dilek Turan, Bulut Yurtsever, Didem Çakırsoy, Selen Abanuz, Muhammet Yılancı, Utku Seyis, Samed Özer, Selin Mert, Cavit Kerem Kayhan, Fatma Tokat, Merve Açıkel Elmas, Selçuk Birdoğan, Serap Arbak, Koray Yalçın, Aslıhan Sezgin, Ebru Kızılkılıç, Cansu Hemşinlioğlu, Ümit İnce, Siret Ratip, Ercüment Ovalı
Format: Article
Language:English
Published: Galenos Publishing House 2020-11-01
Series:Turkish Journal of Hematology
Subjects:
chimeric antigen receptor
cd19
car-t
immunotherapy
Online Access:https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tjh&un=TJH-31391

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https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tjh&un=TJH-31391

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