Polyploid cell dynamics and death before and after PEG-treatment of a NIH/3T3 derived culture: vinblastine effects on the regulation of cell subpopulations heterogeneity

Abstract Background Neoplastic subpopulations can include polyploid cells that can be involved in tumor evolution and recurrence. Their origin can be traced back to the tumor microenvironment or chemotherapeutic treatment, which can alter cell division or favor cell fusion, generating multinucleated...

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Bibliographic Details
Main Authors: Alessandra Spano, Luigi Sciola
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Cell Division
Subjects:
Online Access:https://doi.org/10.1186/s13008-023-00100-y