Molecular Mechanisms of Autophagy Decline during Aging

Macroautophagy (hereafter autophagy) is a cellular recycling process that degrades cytoplasmic components, such as protein aggregates and mitochondria, and is associated with longevity and health in multiple organisms. While mounting evidence supports that autophagy declines with age, the underlying...

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Bibliographic Details
Main Authors: Shaun H. Y. Lim, Malene Hansen, Caroline Kumsta
Format: Article
Language:English
Published: MDPI AG 2024-08-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/13/16/1364