Thalamic deep brain stimulation modulates cycles of seizure risk in epilepsy

Abstract Chronic brain recordings suggest that seizure risk is not uniform, but rather varies systematically relative to daily (circadian) and multiday (multidien) cycles. Here, one human and seven dogs with naturally occurring epilepsy had continuous intracranial EEG (median 298 days) using novel i...

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Bibliographic Details
Main Authors: Nicholas M. Gregg, Vladimir Sladky, Petr Nejedly, Filip Mivalt, Inyong Kim, Irena Balzekas, Beverly K. Sturges, Chelsea Crowe, Edward E. Patterson, Jamie J. Van Gompel, Brian N. Lundstrom, Kent Leyde, Timothy J. Denison, Benjamin H. Brinkmann, Vaclav Kremen, Gregory A. Worrell
Format: Article
Language:English
Published: Nature Portfolio 2021-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-03555-7