Bioengineered yogurt: ‘open source’ medicine

The ease with which commensal bacteria in yogurt can be bioengineered to express an array of biotherapeutics, coupled with altruistic distribution systems that can easily include those, most likely to benefit (think expression of antiplasmodial peptides in the Bifidobacterium genus so that a herder...

Full description

Bibliographic Details
Main Author: Shireesh Apte
Format: Article
Language:English
Published: International Pharmaceutical Excipients Council
Series:Journal of Excipients and Food Chemicals
Online Access:http://jefc.scholasticahq.com/article/1102-bioengineered-yogurt-open-source-medicine.pdf
Description
Summary:The ease with which commensal bacteria in yogurt can be bioengineered to express an array of biotherapeutics, coupled with altruistic distribution systems that can easily include those, most likely to benefit (think expression of antiplasmodial peptides in the Bifidobacterium genus so that a herder in the Sahel can inoculate this yogurt culture into goat milk thus making ‘antimalarial yogurt’ for free for his entire village. This could potentially go on as long as the plasmid is stable) and could lead to a revolution in the way medicines could become ‘open sourced’.
ISSN:2150-2668