Potent Cell-Intrinsic Immune Responses in Dendritic Cells Facilitate HIV-1-Specific T Cell Immunity in HIV-1 Elite Controllers.

The majority of HIV-1 elite controllers (EC) restrict HIV-1 replication through highly functional HIV-1-specific T cell responses, but mechanisms supporting the evolution of effective HIV-1-specific T cell immunity in these patients remain undefined. Cytosolic immune recognition of HIV-1 in conventi...

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Bibliographic Details
Main Authors: Enrique Martin-Gayo, Maria Jose Buzon, Zhengyu Ouyang, Taylor Hickman, Jacqueline Cronin, Dina Pimenova, Bruce D Walker, Mathias Lichterfeld, Xu G Yu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-06-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4466270?pdf=render