Intracellular cGMP increase is not involved in thyroid cancer cell death.

Intracellular cGMP increase is not involved in thyroid cancer cell death.

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<h4>Introduction</h4>Type 5 phosphodiesterase (PDE5) inhibitors (PDE5i) lead to intracellular cyclic-guanosine monophosphate (cGMP) increase and are used for clinical treatment of erectile dysfunction. Studies found that cGMP may up/downregulate the growth of certain endocrine tumor cell...

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Bibliographic Details
Main Authors: Sara D' Alessandro, Elia Paradiso, Clara Lazzaretti, Samantha Sperduti, Carmela Perri, Francesco Antoniani, Sara Righi, Manuela Simoni, Giulia Brigante, Livio Casarini
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0283888

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https://doi.org/10.1371/journal.pone.0283888

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