Membranolytic Activity of Bile Salts: Influence of Biological Membrane Properties and Composition

Membranolytic Activity of Bile Salts: Influence of Biological Membrane Properties and Composition

The two main steps of the membranolytic activity of detergents: 1) the partitioning of detergent molecules in the membrane and 2) the solubilisation of the membrane are systematically investigated. The interactions of two bile salt molecules, sodium cholate (NaC) and sodium deoxycholate (NaDC) with...

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Bibliographic Details
Main Authors: Alfred Blume, Katja Knauf, Annegret Hildebrand, Patrick Garidel
Format: Article
Language:English
Published: MDPI AG 2007-10-01
Series:Molecules
Subjects:
Bile salt
liposome
phospholipid
vesicle
membranolytic
membrane
ITC
partitioning
solubilisation
thermodynamic.
Online Access:http://www.mdpi.com/1420-3049/12/10/2292/

Internet

http://www.mdpi.com/1420-3049/12/10/2292/

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