mTOR contributes to endothelium-dependent vasorelaxation by promoting eNOS expression and preventing eNOS uncoupling
The endothelium-specific inhibition of either of mammalian target of rapamycin (mTOR) complexes impairs endothelial-dependent vasodilatation (EDD), accompanied by decreased nitric oxide bioavailability in both human and mice endothelial cells.
| Hauptverfasser: | , , , , , , , , |
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| Format: | Artikel |
| Sprache: | English |
| Veröffentlicht: |
Nature Portfolio
2022-07-01
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| Schriftenreihe: | Communications Biology |
| Online Zugang: | https://doi.org/10.1038/s42003-022-03653-w |