<i>Maytenus disticha</i> Extract and an Isolated β-Dihydroagarofuran Induce Mitochondrial Depolarization and Apoptosis in Human Cancer Cells by Increasing Mitochondrial Reactive Oxygen Species

<i>Maytenus disticha</i> Extract and an Isolated β-Dihydroagarofuran Induce Mitochondrial Depolarization and Apoptosis in Human Cancer Cells by Increasing Mitochondrial Reactive Oxygen Species

<i>Maytenus disticha</i> (Hook F.), belonging to the Celastraceae family, is an evergreen shrub, native of the central southern mountains of Chile. Previous studies demonstrated that the total extract of <i>M. disticha</i> (MD) has an acetylcholinesterase inhibitory activity...

Full description

Bibliographic Details
Main Authors: Iván González-Chavarría, Felix Duprat, Francisco J. Roa, Nery Jara, Jorge R. Toledo, Felipe Miranda, José Becerra, Alejandro Inostroza, Alexandra Kelling, Uwe Schilde, Matthias Heydenreich, Cristian Paz
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Biomolecules
Subjects:
<i>maytenus disticha</i>
<i>β</i>-dihydroagarofuran-type sesquiterpene
dihydromyricetin
dihydromyricetin-3-o-<i>β</i>-glucoside
cytotoxic activity
mitochondrial ros
Online Access:https://www.mdpi.com/2218-273X/10/3/377

Internet

https://www.mdpi.com/2218-273X/10/3/377

Similar Items