Essential Components of Synthetic Infectious Prion Formation De Novo

Prion diseases are a class of neurodegenerative diseases that are uniquely infectious. Whilst their general replication mechanism is well understood, the components required for the formation and propagation of highly infectious prions are poorly characterized. The protein-only hypothesis posits tha...

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Bibliographic Details
Main Authors: Kezia Jack, Graham S. Jackson, Jan Bieschke
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/12/11/1694