SOPHIE: Generative Neural Networks Separate Common and Specific Transcriptional Responses

SOPHIE: Generative Neural Networks Separate Common and Specific Transcriptional Responses

Genome-wide transcriptome profiling identifies genes that are prone to differential expression (DE) across contexts, as well as genes with changes specific to the experimental manipulation. Distinguishing genes that are specifically changed in a context of interest from common differentially express...

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Bibliographic Details
Main Authors: Alexandra J. Lee, Dallas L. Mould, Jake Crawford, Dongbo Hu, Rani K. Powers, Georgia Doing, James C. Costello, Deborah A. Hogan, Casey S. Greene
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:Genomics, Proteomics & Bioinformatics
Subjects:
Neural network
Transcriptomics
Software
Differential expression analysis
Machine learning
Online Access:http://www.sciencedirect.com/science/article/pii/S1672022922001279

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http://www.sciencedirect.com/science/article/pii/S1672022922001279

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