Development of a Promising <sup>18</sup>F-Radiotracer for PET Imaging Legumain Activity In Vivo

Legumain has been found overexpressed in several cancers, which serves as an important biomarker for cancer diagnosis. In this research, a novel fluorine-18 labeled radioactive tracer [<sup>18</sup>F]<b>SF-AAN</b> targeting legumain was designed and synthesized for positron e...

Full description

Bibliographic Details
Main Authors: Chunmei Lu, Xiuting Wang, Qiqi Wang, Lixia Zhang, Jianguo Lin, Ling Qiu
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Pharmaceuticals
Subjects:
Online Access:https://www.mdpi.com/1424-8247/15/5/543