EIF2α phosphorylation: a hallmark of both autophagy and immunogenic cell death

Different intrinsic and extrinsic stress pathways including endoplasmic reticulum (ER) stress converge on the phosphorylation of eukaryotic translation initiation factor 2A (EIF2A, best known as eIF2α), which characterizes the so-called “integrated stress response”. This phosphorylation event is imp...

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Bibliographic Details
Main Authors: Juliette Humeau, Lucillia Bezu, Oliver Kepp, Guido Kroemer
Format: Article
Language:English
Published: Taylor & Francis Group 2020-09-01
Series:Molecular & Cellular Oncology
Subjects:
Online Access:http://dx.doi.org/10.1080/23723556.2020.1776570