Absolute Configuration Determination of Retroflexanone Using the Advanced Mosher Method and Application of HPLC-NMR

Absolute Configuration Determination of Retroflexanone Using the Advanced Mosher Method and Application of HPLC-NMR

The absolute configuration of retroflexanone (1) and a closely related phlorogluinol (2) was established using the advanced Mosher method and by application of HPLC-NMR. HPLC-NMR permitted a small scale Mosher method analysis to be carried out on these unstable phloroglucinols.

Bibliographic Details
Main Authors:	Caleb Singleton, Robert Brkljača, Sylvia Urban
Format:	Article
Language:	English
Published:	MDPI AG 2018-06-01
Series:	Marine Drugs
Subjects:	Mosher retroflexanone phloroglucinol HPLC-NMR secondary alcohol
Online Access:	http://www.mdpi.com/1660-3397/16/6/205

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