B cell autoimmunity and bone damage in rheumatoid arthritis
Rheumatoid arthritis (RA) is a chronic immune-inflammatory disease associated with significant bone damage. Pathological bone remodeling in RA is primarily driven by persistent inflammation. Indeed, pro-inflammatory cytokines stimulate the differentiation of bone-resorbing osteoclasts and, in parall...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
PAGEPress Publications
2016-12-01
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Series: | Reumatismo |
Subjects: | |
Online Access: | http://www.reumatismo.org/index.php/reuma/article/view/914 |